The A Path to Thriving (APT) project built on the promising work of CASBHC and its partners aiming to improve the quantity and quality of healthcare for Colorado’s vulnerable youth. APT supported with the Foundation’s vision, mission, belief, and cornerstones for achieving health equity. The project worked to align and improve systems within and between health and educational sectors to create a continuum of education, prevention, and intervention that helps youth overcome obstacles to health and have the opportunity to thrive in all aspects of life. CASBHC and Apex worked together to adapt and facilitate a continuous improvement process for administrative and clinical staff. Apex adapted Kaizen practices to make them relevant and feasible in an SBHC setting and applied a Systems Evaluation Protocol (SEP) developed at Cornell University to ensure that APT’s design and implementation were grounded in data-based decision-making. Project activities and grantee engagement resulted in the identification of many priorities for continued development of the Apex Data Hub and Data App. Informed by this project, the tailored data system will continue to support SBHCs through an advancing technology landscape, especially regarding factors amplified by the COVID-19 pandemic, including a desire for real-time data; need for increased collaboration between agencies; importance of remote work, school, and healthcare; and attention to social determinants of health.